Unexplained loss of muscle mass, also known as idiopathic sarcopenia, is a concerning condition where muscle seems to waste away or atrophy for unknown reasons. This troubling symptom goes by several names:
- Cachexia: Generalized weakness and loss of body mass
- Wasting syndrome: Gradual decline in weight and muscle strength
- The condition is diagnosed by exclusion when no other cause for muscle loss can be found. Tests come back normal yet muscle keeps disappearing.
- Both men and women can be affected, usually later in life. Most cases occur in those over 60 years old.
- Weakness affects legs first - trouble standing from a seated position or climbing stairs are common complaints.
- Idiopathic sarcopenia differs from muscle loss due to immobilization, malnutrition, medications, or illnesses.
- Age-related changes in hormones, metabolism, or protein synthesis
- Chronic, low-grade inflammation damaging muscles
- Limitations in blood vessel or nervous system function
- Toxins, infections, or autoimmunity attacking muscles
- Encourage an active lifestyle and weight/resistance training
- Ensure adequate protein intake at meals along with nutrients
- Check for vitamin D deficiency and supplement if low
- Identify and manage conditions that provoke inflammation
- Discuss elimination diets and immunomodulators if autoimmunity suspected
- Consider physical therapy to strengthen muscles safely